| Reaction Details |
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 | Report a problem with these data |
| Target | 1,3-beta-glucan synthase |
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| Ligand | BDBM111591 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Glucan Synthase Assay |
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| pH | 8±n/a |
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| Temperature | 303.15±n/a K |
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| IC50 | 23000±n/a nM |
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| Citation |  Carr, AD; Neuss, JC; Orchard, MG; Porter, DW Substituted aniline derivatives US Patent US8624022 Publication Date 1/7/2014 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| 1,3-beta-glucan synthase |
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| Name: | 1,3-beta-glucan synthase |
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| Synonyms: | Glucan Synthase |
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| Type: | Enzyme |
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| Mol. Mass.: | 218165.65 |
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| Organism: | Neosartorya fumigata (Aspergillus fumigatus) |
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| Description: | Q4WLT4 |
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| Residue: | 1904 |
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| Sequence: | MSGYQQGGGHYNDGYGHQEHGDSFYQDEHGQAYYDHDYGDGYYDRSGYYGPDSNHNQQEG
GYYDAGQPHDDYYGDHYYDQGNGQQGYDNRGRRRGDSEEDSETFSDFTMRSETARAADMD
YYGRGDERYNSYADSQYGGRGYGYRPPSSQISYGANRSSGASTPVYGMDYGNALPAGQRS
REPYPAWASDGQVPVSKEEIEDIFLDLVNKFGFQRDSMRNMYDHLMTMLDSRASRMTPNQ
ALLSLHADYIGGDNANYRRWYFAAHLDLDDAVGFANMKLGKADRKTRKARKAAKKAAQQN
PENVEETLEALEGDNSLEAAEYRWKTRMNKMSQHDRVRQLALFLLCWGEANQVRFLPECL
CFIFKCADDYYNSPECQNRVEPVEEFTYLNEIITPLYQYCRDQGYEIVDGKYVRRERDHN
QIIGYDDMNQLFWYPEGIERIALEDKTRLVDIPPAERWTKLKDVVWKKAFFKTYKETRSW
FHMITNFNRIWVIHLGAFWFFTAFNAQSLYTDNYQQQVNNKPPGYRIWSAVGFGGALVSF
IQIAATICEWMYVPRRWAGAQHLTKRLMFLILVFVINLAPGVFVFAYSKSMGISKTIPLI
VGIVHFFVALATFVFFSVMPLGGLFGSYLKKHGRQYVASQTFTASFPRLHGNDMWMSYGL
WVCVFGAKLAESYFFLTLSFKDPIRILSPMQIHQCAGVKYIGNVLCHKQPQILLGLMFFM
DLTLFFLDSYLWYIICNTVFSVARSFYLGVSIWSPWRNIFSRLPKRIYSKVLATTDMEIK
YKPKVLISQVWNAIIISMYREHLLAIDHVQKLLYHQVPSEQEGKRTLRAPTFFVSQEDQS
FKTEFFPPGSEAERRISFFAQSLSTPMPEPLPVDNMPTFTVLIPHYSEKILLSLREIIRE
DEPYSRVTLLEYLKQLHPHEWDCFVKDTKILADETSQFNGEPEKSEKDVAKSKIDDLPFY
CIGFKSAAPEYTLRTRIWSSLRSQTLYRTVSGFMNYSRAIKLLYRVENPEVVQMFGGNSE
KLERELERMARRKFKIVVSMQRYAKFNKEERENTEFLLRAYPDLQIAYLDEEPPVNEGEE
PRLYSALIDGHCELLENGMRKPKFRIQLSGNPILGDGKSDNQNHSIIFYRGEYIQVIDAN
QDNYLEECLKIRSVLAEFEELTTDNVSPYTPGIPSTNTNPVAILGAREYIFSENIGVLGD
VAAGKEQTFGTLFARTLAQIGGKLHYGHPDFLNGIFMTTRGGISKAQKGLHLNEDIYAGM
NAMIRGGRIKHCEYYQCGKGRDLGFGSILNFTTKIGTGMGEQMLSREYYYLGTQLPLDRF
LSFYYAHPGFHINNMFIMLSVQMFMIVLINLGALKHETITCRYNPDLPITDPLRPTYCAN
LTPIVDWVNRCIISIFIVFFISFVPLAVQELTERGVWRMAMRLAKHFGSVSFMFEVFVCQ
IYANAVHQNLSFGGARYIGTGRGFATARIPFGVLYSRFAGPSIYAGARSLLMLLFATSTV
WTAALIWFWVSLLALCISPFLFNPHQFAWNDFFIDYRDYLRWLSRGNSRSHASSWIGFCR
LSRTRITGYKRKLLGVPSEKGSGDVPRARLTNIFFSEIIAPLVLVAVTLVPYLYINSRTG
VRDNPEPTDAILRLAIVAAGPIAINAGVAGVFFGMACCMGPIFSMCCKKFGAVLAAIAHA
IAVIVLLAIFEVMFFLESWSWPRMLIGMIAAAAIQRFIYKLIIALALTREFKHDQSNIAW
WTGKWYNMGWHSMSQPGREFLCKITELGYFSADFVLGHVLLFAMLPALCVPFIDKFHSVM
LFWLRPSRQIRPPIYSLKQSKLRKRRVIRFAILYFGMLILFLVLLIAPLVVRSMGLVKTP
NLPFNLLQPLDKDNNDTMVTYTGNNIPAGFEPVESASSVATATS
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| BDBM111591 |
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| n/a |
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| Name | BDBM111591 |
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| Synonyms: | US8624022, OGT4355 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H31N3O2 |
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| Mol. Mass. | 453.5753 |
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| SMILES | CCc1cccc(c1)-c1ccc(cc1)N(CC(=O)N1CC[C@H](N)C1)C(=O)\C=C\c1ccccc1 |r| |
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| Structure | 
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