Reaction Details |
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Target | Nuclear hormone receptor family member daf-12 |
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Ligand | BDBM114772 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12) |
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EC50 | 67541±n/a nM |
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Citation | PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify agonists of the DAF-12 from the parasite H. contortus (hcDAF-12) PubChem Bioassay(2013)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Nuclear hormone receptor family member daf-12 |
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Name: | Nuclear hormone receptor family member daf-12 |
Synonyms: | DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 84211.49 |
Organism: | Caenorhabditis elegans |
Description: | gi_71987181 |
Residue: | 753 |
Sequence: | MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQM
STPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRV
CGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFT
VGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYP
PQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLT
MMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLM
NEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIP
GNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAM
IPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQ
MQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGV
TRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAV
YLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALG
LLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
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BDBM114772 |
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n/a |
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Name | BDBM114772 |
Synonyms: | (2Z)-2-(phenylhydrazinylidene)-1-benzothiophen-3-one | (2Z)-2-(phenylhydrazono)benzothiophen-3-one | 2-(Phenyl-hydrazono)-benzo[b]thiophen-3-one | MLS000777106 | SMR000413502 | cid_5419037 |
Type | Small organic molecule |
Emp. Form. | C14H10N2OS |
Mol. Mass. | 254.307 |
SMILES | Oc1c(N=Nc2ccccc2)sc2ccccc12 |w:3.2| |
Structure |
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