| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear hormone receptor family member daf-12 |
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| Ligand | BDBM49189 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) |
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| IC50 | 67529±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nuclear hormone receptor family member daf-12 |
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| Name: | Nuclear hormone receptor family member daf-12 |
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| Synonyms: | DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 84211.49 |
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| Organism: | Caenorhabditis elegans |
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| Description: | gi_71987181 |
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| Residue: | 753 |
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| Sequence: | MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQM
STPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRV
CGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFT
VGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYP
PQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLT
MMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLM
NEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIP
GNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAM
IPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQ
MQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGV
TRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAV
YLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALG
LLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
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| BDBM49189 |
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| n/a |
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| Name | BDBM49189 |
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| Synonyms: | 2-(2-pyridinylmethylthio)-3-quinolinecarbonitrile | 2-(2-pyridylmethylthio)quinoline-3-carbonitrile | 2-(Pyridin-2-ylmethylsulfanyl)-quinoline-3-carbonitrile | 2-(pyridin-2-ylmethylsulfanyl)quinoline-3-carbonitrile | MLS000076502 | SMR000007876 | cid_656038 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11N3S |
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| Mol. Mass. | 277.344 |
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| SMILES | N#Cc1cc2ccccc2nc1SCc1ccccn1 |
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| Structure | 
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