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TargetNuclear hormone receptor family member daf-12
LigandBDBM39548
Substrate/Competitorn/a
Meas. Tech.Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12)
IC50 67502±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Nuclear hormone receptor family member daf-12
Name:Nuclear hormone receptor family member daf-12
Synonyms:DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7
Type:Enzyme Catalytic Domain
Mol. Mass.:84211.49
Organism:Caenorhabditis elegans
Description:gi_71987181
Residue:753
Sequence:
MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQM
STPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRV
CGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFT
VGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYP
PQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLT
MMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLM
NEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIP
GNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAM
IPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQ
MQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGV
TRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAV
YLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALG
LLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
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  Blast E-value cutoff:
BDBM39548
n/a
NameBDBM39548
Synonyms:(2-phenyl-1,3-thiazol-4-yl)methyl 1-methylpyrrole-2-carboxylate | 1-methyl-2-pyrrolecarboxylic acid (2-phenyl-4-thiazolyl)methyl ester | 1-methylpyrrole-2-carboxylic acid (2-phenylthiazol-4-yl)methyl ester | MLS000058002 | SMR000063048 | cid_2091642
TypeSmall organic molecule
Emp. Form.C16H14N2O2S
Mol. Mass.298.36
SMILESCn1cccc1C(=O)OCc1csc(n1)-c1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: