| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear hormone receptor family member daf-12 |
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| Ligand | BDBM114935 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) |
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| IC50 | 67491±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nuclear hormone receptor family member daf-12 |
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| Name: | Nuclear hormone receptor family member daf-12 |
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| Synonyms: | DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 84211.49 |
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| Organism: | Caenorhabditis elegans |
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| Description: | gi_71987181 |
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| Residue: | 753 |
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| Sequence: | MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQM
STPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRV
CGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFT
VGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYP
PQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLT
MMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLM
NEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIP
GNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAM
IPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQ
MQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGV
TRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAV
YLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALG
LLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK
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| BDBM114935 |
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| n/a |
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| Name | BDBM114935 |
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| Synonyms: | MLS001174493 | N-(2,3-dihydro-1H-inden-5-yl)-2-methoxy-4-(methylthio)benzamide | N-(2,3-dihydro-1H-inden-5-yl)-2-methoxy-4-methylsulfanyl-benzamide | N-(2,3-dihydro-1H-inden-5-yl)-2-methoxy-4-methylsulfanylbenzamide | N-indan-5-yl-2-methoxy-4-(methylthio)benzamide | SMR000588656 | cid_2124983 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19NO2S |
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| Mol. Mass. | 313.414 |
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| SMILES | COc1cc(SC)ccc1C(=O)Nc1ccc2CCCc2c1 |
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| Structure | 
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