Ki Summary

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Target

Nuclear hormone receptor family member daf-12

Ligand

BDBM77929

Substrate/Competitor

n/a

Meas. Tech.

Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12)

IC50

67399±n/a nM

Citation

PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of the DAF-12 from the parasite S. stercoralis (ssDAF-12) PubChem Bioassay(2013)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Nuclear hormone receptor family member daf-12

Name:

Nuclear hormone receptor family member daf-12

Synonyms:

DAF12_CAEEL | Protein DAF-12, isoform a | XL285 | daf-12 | daf-20 | mig-7

Type:

Enzyme Catalytic Domain

Mol. Mass.:

84211.49

Organism:

Caenorhabditis elegans

Description:

gi_71987181

Residue:

753

Sequence:

MGTNGGVIAEQSMEIETNENPDKVEEPVVRRKRVTRRRHRRIHSKNNCLTPPNSDDDPQM
STPDDPVIHSPPSIGAAPGMNGYHGSGVKLEESSGACGSPDDGLLDSSEESRRRQKTCRV
CGDHATGYNFNVITCESCKAFFRRNALRPKEFKCPYSEDCEINSVSRRFCQKCRLRKCFT
VGMKKEWILNEEQLRRRKNSRLNNTGTCNKRSQPGNQQSPQGPNQQPHLSPHHPGVAIYP
PQPQRPLTINPMDNQMMHHMQANRPNAMPQLISPPGAQPYPLTSPVGSSASDSPPNRSLT
MMHNGEKSPDGYDPNIMAHRAPPPSFNNRPKMDSGQVVLSTEEYKQLLSRIPGAQVPGLM
NEEEPINKRAAYNCNGHPMPAETTPPYSAPMSDMSLSRHNSTSSGTEKNHMTHSTVSAIP
GNSAQNHFDIASFGMGIVTATGGGDAAEEMYKRMNMFYENCIQSALDSPENQEPKPQEAM
IPKEEYMTPTHGFQYQSDPYQVPPAERNINYQLNAAELKALDAVREAFYGMDDPMEQGRQ
MQSFLKANKTPADIMNIMDVTMRRFVKVAKGVPAFREVSQEGKFSLLKGGMIEMLTVRGV
TRYDASTNSFKTPTIKGQNVSVNVDDMFAKLNANAQAQKAKCLEFFGFFDEEIKKNELAV
YLVMLAVLFSVRSDPPMNENDVRIVTERHNHFMSLLNRYLESLFGEQARRIFERIPKALG
LLNEIARNAGMLFMGTVRSGEAEELPGEFFKIK

BDBM77929

n/a

Name

BDBM77929

Synonyms:

MLS002174170 | SMR001261337 | cid_25102468

Type

Small organic molecule

Emp. Form.

C26H21ClN2O3

Mol. Mass.

444.91

SMILES

[H][C@]12COc3ccccc3[C@]1([H])N1C(=O)c3cc(Cl)ccc3NC(=O)[C@@]1(C)[C@H]2c1ccccc1

Structure