Reaction Details | |||
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Target | Nociceptin receptor | ||
Ligand | BDBM116206 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ORL-1 Receptor Binding Assay | ||
pH | 7.4±n/a | ||
Temperature | 277.15±n/a K | ||
Ki | 610±n/a nM | ||
Comments | extracted | ||
Citation | Brown, KC; Goehring, RR 2,3,4,5-tetrahydro-benzo{B}{1,4}diazepine-comprising compounds of formula(III) for treating pain US Patent US8637502 Publication Date 1/28/2014 | ||
More Info.: | Get all data from this article, Assay Method | ||
Nociceptin receptor | |||
Name: | Nociceptin receptor | ||
Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 40702.87 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P41146 | ||
Residue: | 370 | ||
Sequence: |
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BDBM116206 | |||
n/a | |||
Name | BDBM116206 | ||
Synonyms: | US8637502, 10 | ||
Type | Small organic molecule | ||
Emp. Form. | C23H33N3O2 | ||
Mol. Mass. | 383.527 | ||
SMILES | CC(C)C1CCC(CC1)N1CCC(CC1)N1c2ccccc2NC(=O)CC1=O |(2.14,-8.13,;.8,-7.36,;-.53,-8.13,;.8,-5.82,;-.53,-5.05,;-.53,-3.51,;.8,-2.74,;2.14,-3.51,;2.14,-5.05,;.8,-1.2,;-.53,-.43,;-.53,1.11,;.8,1.88,;2.14,1.11,;2.14,-.43,;.8,3.42,;-.58,4.09,;-1.71,3.04,;-3.18,3.5,;-3.52,5,;-2.39,6.05,;-.92,5.59,;.04,6.8,;1.58,6.8,;2.35,8.13,;2.54,5.59,;2.19,4.09,;3.52,3.32,)| | ||
Structure |