| Reaction Details |
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 | Report a problem with these data |
| Target | Transthyretin |
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| Ligand | BDBM128211 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription |
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| EC50 | >167158±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Transthyretin |
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| Name: | Transthyretin |
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| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15884.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P02766 |
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| Residue: | 147 |
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| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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| BDBM128211 |
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| n/a |
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| Name | BDBM128211 |
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| Synonyms: | 7-[(4-hydroxyphenyl)-[(6-methyl-2-pyridinyl)amino]methyl]-2-methyl-8-quinolinol | 7-[(4-hydroxyphenyl)-[(6-methyl-2-pyridyl)amino]methyl]-2-methyl-quinolin-8-ol | 7-[(4-hydroxyphenyl)-[(6-methylpyridin-2-yl)amino]methyl]-2-methyl-quinolin-8-ol | 7-[(4-hydroxyphenyl)-[(6-methylpyridin-2-yl)amino]methyl]-2-methylquinolin-8-ol | 7-{(4-hydroxyphenyl)[(6-methyl-2-pyridinyl)amino]methyl}-2-methyl-8-quinolinol | MLS000530643 | SMR000135621 | cid_2895747 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21N3O2 |
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| Mol. Mass. | 371.4317 |
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| SMILES | Cc1cccc(NC(c2ccc(O)cc2)c2ccc3ccc(C)nc3c2O)n1 |
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| Structure | 
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