BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetTransthyretin
LigandBDBM96956
Substrate/Competitorn/a
Meas. Tech.Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50>167158±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay(2014)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Transthyretin
Name:Transthyretin
Synonyms:ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:Enzyme
Mol. Mass.:15884.31
Organism:Homo sapiens (Human)
Description:P02766
Residue:147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM96956
n/a
NameBDBM96956
Synonyms:4-(1,3-benzothiazol-2-yl)-N-(5-methyl-1,3-thiazol-2-yl)butanamide | 4-(1,3-benzothiazol-2-yl)-N-(5-methyl-2-thiazolyl)butanamide | 4-(1,3-benzothiazol-2-yl)-N-(5-methylthiazol-2-yl)butyramide | MLS000568842 | SMR000154827 | cid_2445782
TypeSmall organic molecule
Emp. Form.C15H15N3OS2
Mol. Mass.317.429
SMILESCc1cnc(NC(=O)CCCc2nc3ccccc3s2)s1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: