Reaction Details |
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Target | Transthyretin |
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Ligand | BDBM128221 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription |
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EC50 | >167158±n/a nM |
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Citation | PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay(2014)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Transthyretin |
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Name: | Transthyretin |
Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
Type: | Enzyme |
Mol. Mass.: | 15884.31 |
Organism: | Homo sapiens (Human) |
Description: | P02766 |
Residue: | 147 |
Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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BDBM128221 |
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n/a |
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Name | BDBM128221 |
Synonyms: | (1,5-dimethylpyrazol-4-yl)-indolin-1-yl-methanone | 1-[(1,5-dimethyl-1H-pyrazol-4-yl)carbonyl]indoline | 2,3-dihydroindol-1-yl-(1,5-dimethyl-4-pyrazolyl)methanone | 2,3-dihydroindol-1-yl-(1,5-dimethylpyrazol-4-yl)methanone | MLS000698295 | SMR000227824 | cid_1225706 |
Type | Small organic molecule |
Emp. Form. | C14H15N3O |
Mol. Mass. | 241.2884 |
SMILES | Cc1c(cnn1C)C(=O)N1CCc2ccccc12 |
Structure |
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