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Reaction Details
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TargetTransthyretin
LigandBDBM128232
Substrate/Competitorn/a
Meas. Tech.Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50>167158±n/a nM
Citation PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay(2014)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Transthyretin
Name:Transthyretin
Synonyms:ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:Enzyme
Mol. Mass.:15884.31
Organism:Homo sapiens (Human)
Description:P02766
Residue:147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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  Blast E-value cutoff:
BDBM128232
n/a
NameBDBM128232
Synonyms:3-(3,4-Dimethoxy-phenyl)-5-thiophen-2-yl-[1,2,4]oxadiazole | 3-(3,4-dimethoxyphenyl)-5-(2-thienyl)-1,2,4-oxadiazole | 3-(3,4-dimethoxyphenyl)-5-thiophen-2-yl-1,2,4-oxadiazole | MLS000333489 | SMR000437691 | cid_1221653
TypeSmall organic molecule
Emp. Form.C14H12N2O3S
Mol. Mass.288.322
SMILESCOc1ccc(cc1OC)-c1noc(n1)-c1cccs1
Structure
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