| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transthyretin |
|---|
| Ligand | BDBM128235 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription |
|---|
| EC50 | >167158±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay(2014)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Transthyretin |
|---|
| Name: | Transthyretin |
|---|
| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 15884.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P02766 |
|---|
| Residue: | 147 |
|---|
| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
|
|
|
|---|
| BDBM128235 |
|---|
| n/a |
|---|
| Name | BDBM128235 |
|---|
| Synonyms: | 2,5-bis[(dimethylamino)methyl]-1,1,6,6-tetraphenyl-hexane-1,6-diol | 2,5-bis[(dimethylamino)methyl]-1,1,6,6-tetraphenylhexane-1,6-diol | MLS001173677 | SMR000538747 | cid_3781244 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C36H44N2O2 |
|---|
| Mol. Mass. | 536.7468 |
|---|
| SMILES | CN(C)CC(CCC(CN(C)C)C(O)(c1ccccc1)c1ccccc1)C(O)(c1ccccc1)c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
