| Reaction Details |
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 | Report a problem with these data |
| Target | Transthyretin |
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| Ligand | BDBM128241 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription |
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| EC50 | >167158±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay(2014)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Transthyretin |
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| Name: | Transthyretin |
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| Synonyms: | ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR) |
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| Type: | Enzyme |
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| Mol. Mass.: | 15884.31 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P02766 |
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| Residue: | 147 |
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| Sequence: | MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT
WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDS
GPRRYTIAALLSPYSYSTTAVVTNPKE
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| BDBM128241 |
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| n/a |
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| Name | BDBM128241 |
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| Synonyms: | (2,3-dimethylphenyl)-[3-(4-fluorophenyl)isoxazolo[5,4-d]pyrimidin-4-yl]-methyl-amine | MLS001143290 | N-(2,3-dimethylphenyl)-3-(4-fluorophenyl)-N-methyl-4-isoxazolo[5,4-d]pyrimidinamine | N-(2,3-dimethylphenyl)-3-(4-fluorophenyl)-N-methyl-[1,2]oxazolo[5,4-d]pyrimidin-4-amine | SMR000796266 | cid_24856208 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H17FN4O |
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| Mol. Mass. | 348.3736 |
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| SMILES | CN(c1cccc(C)c1C)c1ncnc2onc(-c3ccc(F)cc3)c12 |
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| Structure | 
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