| Reaction Details |
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 | Report a problem with these data |
| Target | Chymase |
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| Ligand | BDBM134255 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibitory Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 30±n/a nM |
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| Comments | extracted |
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| Citation |  Muto, T; Tanaka, T; Futamura, J; Imajo, S; Sugawara, H Seven-membered ring compound and pharmaceutical use therefor US Patent US8846660 Publication Date 9/30/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| Chymase |
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| Name: | Chymase |
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| Synonyms: | Alpha-chymase | CMA1 | CMA1_HUMAN | CYH | CYM | Chymase precursor | Mast cell protease I |
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| Type: | Enzyme |
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| Mol. Mass.: | 27340.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 247 |
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| Sequence: | MLLLPLPLLLFLLCSRAEAGEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNF
VLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKA
SLTLAVGTLPFPSQFNFVPPGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRD
FDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSDAKPPAVFTRISHYRPWI
NQILQAN
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| BDBM134255 |
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| n/a |
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| Name | BDBM134255 |
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| Synonyms: | US8846660, 15 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H36ClN5O6 |
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| Mol. Mass. | 574.068 |
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| SMILES | CCC[C@@H](NC(=O)N1C\C(NCC(Cc2cc(Cl)ccc2OC)C1=O)=N\OC(C)C)c1ccc(C(O)=O)c(N)c1 |r| |
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| Structure | 
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