| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin K |
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| Ligand | BDBM139527 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhbition Assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 1100±n/a nM |
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| Comments | extracted |
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| Citation |  Grauert, M; Anderskewitz, R; Grundl, M; Oost, T; Pautsch, A; Peters, S Substituted bicyclic 1-carboxylic-acid (benzyl-cyano-methyl)-amides inhibitors of cathepsin C US Patent US8889708 Publication Date 11/18/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Cathepsin K |
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| Name: | Cathepsin K |
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| Synonyms: | CATK_HUMAN | CTSK | CTSO | CTSO2 | Cathepsin O | Cathepsin O2 | Cathepsin X |
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| Type: | Enzyme |
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| Mol. Mass.: | 36975.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43235 |
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| Residue: | 329 |
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| Sequence: | MWGLKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIH
NLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVD
YRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGG
YMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVA
RVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGE
NWGNKGYILMARNKNNACGIANLASFPKM
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|
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| BDBM139527 |
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| n/a |
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| Name | BDBM139527 |
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| Synonyms: | US8889708, 26 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H31FN4O3 |
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| Mol. Mass. | 490.5691 |
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| SMILES | n/a |
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| Structure | 
|
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