Ki Summary

Reaction Details

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Target

D(3) dopamine receptor

Ligand

BDBM141816

Substrate/Competitor

n/a

Meas. Tech.

Radioligand Binding Assay

2.79±n/a nM

Citation

Rodriguez Sarmiento, RM; Wichmann, J Benzofurane-piperidine compounds US Patent US8921397 Publication Date 12/30/2014

More Info.:

Get all data from this article, Assay Method

D(3) dopamine receptor

Name:

D(3) dopamine receptor

Synonyms:

Type:

n/a

Mol. Mass.:

44243.43

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

400

Sequence:

MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC

BDBM141816

n/a

Name

BDBM141816

Synonyms:

US8921397, 58

Type

Small organic molecule

Emp. Form.

C29H34N2O4

Mol. Mass.

474.5913

SMILES

O=C(N[C@H]1CC[C@H](CCN2CCC(CC2)c2coc3ccccc23)CC1)c1ccc2OCOc2c1 |r,wU:6.6,wD:3.2,(4.77,2.67,;5.54,1.33,;4.77,,;3.23,,;2.46,1.33,;.92,1.33,;.15,,;-1.39,,;-2.16,-1.33,;-3.7,-1.33,;-4.47,,;-6.01,,;-6.78,-1.33,;-6.01,-2.67,;-4.47,-2.67,;-8.32,-1.33,;-9.22,-2.58,;-10.69,-2.1,;-10.69,-.56,;-11.83,.47,;-11.51,1.97,;-10.05,2.45,;-8.9,1.42,;-9.22,-.09,;.92,-1.33,;2.46,-1.33,;7.08,1.33,;7.85,2.67,;9.39,2.67,;10.16,1.33,;11.67,1.01,;11.83,-.52,;10.42,-1.14,;9.39,,;7.85,,)|

Structure