Reaction Details | |||
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Target | 5-hydroxytryptamine receptor 3A | ||
Ligand | BDBM160714 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Radioligand Binding Assay | ||
pH | 7.5±n/a | ||
Temperature | 298.15±n/a K | ||
Ki | 6±n/a nM | ||
Comments | extracted | ||
Citation | Guzzo, PR; Manning, DD; Earley, W 5-HT3 receptor modulators, methods of making, and use thereof US Patent US9045501 Publication Date 6/2/2015 | ||
More Info.: | Get all data from this article, Assay Method | ||
5-hydroxytryptamine receptor 3A | |||
Name: | 5-hydroxytryptamine receptor 3A | ||
Synonyms: | 5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3 | ||
Type: | Protein | ||
Mol. Mass.: | 55283.27 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P46098 | ||
Residue: | 478 | ||
Sequence: |
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BDBM160714 | |||
n/a | |||
Name | BDBM160714 | ||
Synonyms: | US9045501, 9 | ||
Type | Small organic molecule | ||
Emp. Form. | C17H19FN4O | ||
Mol. Mass. | 314.3574 | ||
SMILES | Fc1cc2C(=O)N(CCn3ncc(c1)c23)C1CN2CCC1CC2 |(-3.19,-5.12,;-1.85,-4.35,;-1.85,-2.81,;-.52,-2.04,;-.75,-.54,;-2.24,-.14,;.21,.66,;1.75,.66,;2.71,-.54,;2.28,-2.34,;3.19,-3.58,;2.28,-4.83,;.82,-4.35,;-.52,-5.12,;.82,-2.81,;-.19,2.15,;-1.68,2.55,;-2.08,4.04,;-.99,5.12,;.5,4.73,;.9,3.24,;-.59,2.84,;-.59,4.43,)| | ||
Structure |