| Reaction Details |
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 | Report a problem with these data |
| Target | Mitogen-activated protein kinase 1 [T157A] |
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| Ligand | BDBM176673 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence Quenching Assay |
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| Kd | 2400±400 nM |
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| Citation |  Shapiro, PS; MacKerell, Jr., AD; Fletcher, S Non-ATP dependent inhibitors of extracellular signal-regulated kinase (ERK) US Patent US9115122 Publication Date 8/25/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Mitogen-activated protein kinase 1 [T157A] |
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| Name: | Mitogen-activated protein kinase 1 [T157A] |
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| Synonyms: | ERK2(T157A) | Erk2 | MK01_MOUSE | Mapk | Mapk1 | Prkm1 |
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| Type: | n/a |
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| Mol. Mass.: | 41248.63 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P63085[T157A] |
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| Residue: | 358 |
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| Sequence: | MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQ
TYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLS
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNATCDLKICDFGLARVADPDHDHTG
FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG
ILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRI
EVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
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| BDBM176673 |
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| n/a |
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| Name | BDBM176673 |
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| Synonyms: | US9115122, 76.2 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N2OS2 |
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| Mol. Mass. | 290.404 |
|---|
| SMILES | NCCN1C(=S)S\C(=C/C=C/c2ccccc2)C1=O |
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| Structure | 
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