| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase |
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| Ligand | BDBM24778 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MAO Inhibition Assay |
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| IC50 | 3.02e+3± 638 nM |
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| Citation |  Mostert, S; Petzer, A; Petzer, JP Evaluation of Natural and Synthetic 1,4-naphthoquinones as Inhibitors of Monoamine Oxidase. Chem Biol Drug Des87:737-46 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase |
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| Name: | Amine oxidase |
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| Synonyms: | Monoamine oxidase B (MAO-B) |
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| Type: | Protein |
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| Mol. Mass.: | 58780.23 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDHVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIQSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM24778 |
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| n/a |
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| Name | BDBM24778 |
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| Synonyms: | 2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-methyl-1,4-naphthoquinone, 5 | CHEMBL590 | Menadione | Menadione (5d) | Menadione (Vitamin K3) | Menadione, 9 | Vitamin K3 | cid_4055 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H8O2 |
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| Mol. Mass. | 172.18 |
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| SMILES | CC1=CC(=O)c2ccccc2C1=O |t:1| |
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| Structure | 
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