Reaction Details |
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Target | Quinolone signal response protein |
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Ligand | BDBM185153 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Isothermal Titration Calorimetry (ITC) |
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Temperature | 287.15±n/a K |
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Kd | 9e+2± 3e+2 nM |
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Comments | extracted |
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Citation | Zender, M; Witzgall, F; Drees, SL; Weidel, E; Maurer, CK; Fetzner, S; Blankenfeldt, W; Empting, M; Hartmann, RW Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds. ACS Chem Biol11:1755-63 (2016) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Quinolone signal response protein |
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Name: | Quinolone signal response protein |
Synonyms: | Thioesterase PqsE (PqsE) |
Type: | Protein |
Mol. Mass.: | 34298.34 |
Organism: | Pseudomonas aeruginosa PAO1 |
Description: | n/a |
Residue: | 301 |
Sequence: | MLRLSAPGQLDDDLCLLGDVQVPVFLLRLGEASWALVEGGISRDAELVWADLCRWVADPS
QVHYWLITHKHYDHCGLLPYLCPRLPNVQVLASERTCQAWKSESAVRVVERLNRQLLRAE
QRLPEACAWDALPVRAVADGEWLELGPRHRLQVIEAHGHSDDHVVFYDVRRRRLFCGDAL
GEFDEAEGVWRPLVFDDMEAYLESLERLQRLPTLLQLIPGHGGLLRGRLAADGAESAYTE
CLRLCRRLLWRQSMGESLDELSEELHRAWGGQSVDFLPGELHLGSMRRMLEILSRQALPL
D
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BDBM185153 |
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n/a |
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Name | BDBM185153 |
Synonyms: | CC41801 (1) |
Type | Small organic molecule |
Emp. Form. | C12H9NO2 |
Mol. Mass. | 199.2054 |
SMILES | OC(=O)c1ccccc1-c1cccnc1 |
Structure |
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