| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM192459 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Cellular In Vitro Assay |
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| IC50 | 29±n/a nM |
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| Citation |  Furstner, C; Keldenich, J; Delbeck, M; Kolkhof, P; Kretschmer, A; Pluschkell, I; Pook, E; Schmeck, C; Trubel, H Bisaryl-bonded aryltriazolones and use thereof US Patent US9187466 Publication Date 11/17/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 46820.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37288 |
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| Residue: | 418 |
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| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
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| BDBM192459 |
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| n/a |
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| Name | BDBM192459 |
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| Synonyms: | US9187466, 78 | US9687476, 78 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H15Cl2F3N4O2S |
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| Mol. Mass. | 515.336 |
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| SMILES | O[C@@H](Cn1c(nn(Cc2ncc(s2)-c2ccccc2Cl)c1=O)-c1ccc(Cl)cc1)C(F)(F)F |r| |
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| Structure | 
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