| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Hypoxanthine-guanine phosphoribosyltransferase |
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| Ligand | BDBM60887 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Growth Inhibition Assay |
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| Temperature | 310.15±n/a K |
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| Ki | >200000±n/a nM |
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| Comments | extracted |
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| Citation |  De Jersey, J; Guddat, LW; Hockova, D; Keough, DT 6-oxopurine phosphoribosyltransferase inhibitors US Patent US9200020 Publication Date 12/1/2015 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Hypoxanthine-guanine phosphoribosyltransferase |
|---|
| Name: | Hypoxanthine-guanine phosphoribosyltransferase |
|---|
| Synonyms: | HGPRT | HGPRTase | HPRT | HPRT1 | HPRT_HUMAN | Hypoxanthine-guanine phosphoribosyltransferase | Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) |
|---|
| Type: | Protein |
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| Mol. Mass.: | 24579.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P00492 |
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| Residue: | 218 |
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| Sequence: | MATRSPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGH
HIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSYCNDQSTGDIKVIGGD
DLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVG
FEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA
|
|
|
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| BDBM60887 |
|---|
| n/a |
|---|
| Name | BDBM60887 |
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| Synonyms: | US9200020, Table 3, Compound 2B |
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| Type | n/a |
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| Emp. Form. | C13H21N5O6P |
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| Mol. Mass. | 374.3095 |
|---|
| SMILES | COC(=O)CCN(CCn1c[nH]c2c1nc[nH]c2=O)CCP(O)(O)=O |
|---|
| Structure | 
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