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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cystic fibrosis transmembrane conductance regulator | ||
| Ligand | BDBM50011036 | ||
| Substrate/Competitor | n/a | ||
| EC50 | >50000±n/a nM | ||
| Citation |  PubChem, PC Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in HeLa Cells PubChem Bioassay(2016)[AID] | ||
| More Info.: | Get all data from this article | ||
| Cystic fibrosis transmembrane conductance regulator | |||
| Name: | Cystic fibrosis transmembrane conductance regulator | ||
| Synonyms: | ABCC7 | ATP-binding cassette sub-family C member 7 | CFTR | CFTR_HUMAN | Channel conductance-controlling ATPase | cAMP-dependent chloride channel | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 168171.30 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_90421313 | ||
| Residue: | 1480 | ||
| Sequence: |
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| BDBM50011036 | |||
| n/a | |||
| Name | BDBM50011036 | ||
| Synonyms: | (S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate | (S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester | 2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester | 2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin) | 2-Methyl-butyric acid 8-[2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(Compactin) | CHEMBL54440 | MEVASTATIN | cid_64715 | compactin | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H34O5 | ||
| Mol. Mass. | 390.5131 | ||
| SMILES | CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 |r,c:12,t:10| | ||
| Structure | 
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