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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cystic fibrosis transmembrane conductance regulator | ||
| Ligand | BDBM50228080 | ||
| Substrate/Competitor | n/a | ||
| EC50 | >50000±n/a nM | ||
| Citation |  PubChem, PC Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in HeLa Cells PubChem Bioassay(2016)[AID] | ||
| More Info.: | Get all data from this article | ||
| Cystic fibrosis transmembrane conductance regulator | |||
| Name: | Cystic fibrosis transmembrane conductance regulator | ||
| Synonyms: | ABCC7 | ATP-binding cassette sub-family C member 7 | CFTR | CFTR_HUMAN | Channel conductance-controlling ATPase | cAMP-dependent chloride channel | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 168171.30 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_90421313 | ||
| Residue: | 1480 | ||
| Sequence: |
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| BDBM50228080 | |||
| n/a | |||
| Name | BDBM50228080 | ||
| Synonyms: | 2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate | 2',15'-dimethyl-5,5'-dioxospiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate | 2',15'-dimethyl-5,5'-dioxospiro[tetrahydrofuran-2,14'-tetracyclo[8.7.0.02,7.011,15]heptadec-6'-ene]-9-yl ethanethioate(Spiranolactone) | Aldactone | CHEMBL1393 | S-(2'R,7R,8R,9S,10R,13S,14S)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-7-yl ethanethioate | SPIRONOLACTONE | Spiranolactone | cid_5833 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H32O4S | ||
| Mol. Mass. | 416.573 | ||
| SMILES | CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]2CC[C@@]3(C)[C@@H](CC[C@@]33CCC(=O)O3)[C@H]12 |r,t:6| | ||
| Structure | 
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