| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-synuclein |
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| Ligand | BDBM207853 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | In Vitro Inhibition Assay |
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| EC50 | 78±n/a nM |
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| Citation |  Griffioen, G; Van Dooren, T; Rojas De La Parra, V; Allasia, S; Marchand, A; Kilonda, A; Chaltin, P Compounds for the treatment of neurodegenerative diseases US Patent US9266832 Publication Date 2/23/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Alpha-synuclein |
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| Name: | Alpha-synuclein |
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| Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
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| Type: | Protein |
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| Mol. Mass.: | 14451.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37840 |
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| Residue: | 140 |
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| Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
|
|
|
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| BDBM207853 |
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| n/a |
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| Name | BDBM207853 |
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| Synonyms: | US9266832, Cpd010 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H21ClN2O |
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| Mol. Mass. | 388.889 |
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| SMILES | Clc1ccc2[nH]cc(CCNC(=O)c3cccc(Cc4ccccc4)c3)c2c1 |
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| Structure | 
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