Reaction Details |
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Target | Alpha-synuclein |
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Ligand | BDBM207888 |
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Substrate/Competitor | n/a |
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Meas. Tech. | In Vitro Inhibition Assay |
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EC50 | 22±n/a nM |
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Citation | Griffioen, G; Van Dooren, T; Rojas De La Parra, V; Allasia, S; Marchand, A; Kilonda, A; Chaltin, P Compounds for the treatment of neurodegenerative diseases US Patent US9266832 Publication Date 2/23/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Alpha-synuclein |
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Name: | Alpha-synuclein |
Synonyms: | NACP | PARK1 | SNCA | SYUA_HUMAN |
Type: | Protein |
Mol. Mass.: | 14451.42 |
Organism: | Homo sapiens (Human) |
Description: | P37840 |
Residue: | 140 |
Sequence: | MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTK
EQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDP
DNEAYEMPSEEGYQDYEPEA
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BDBM207888 |
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n/a |
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Name | BDBM207888 |
Synonyms: | US9266832, Cpd045 |
Type | Small organic molecule |
Emp. Form. | C24H20Cl2N2O |
Mol. Mass. | 423.334 |
SMILES | Clc1ccc(Cc2ccc(cc2)C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1 |
Structure |
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