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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209513 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
| ||
| BDBM209513 | |||
| n/a | |||
| Name | BDBM209513 | ||
| Synonyms: | US9271969, 1 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H28F3N3O4 | ||
| Mol. Mass. | 551.5562 | ||
| SMILES | OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccc(OC(F)(F)F)cc1 |r,wD:4.3,(11.99,-6.41,;10.65,-5.64,;10.65,-4.1,;9.32,-6.41,;7.98,-5.64,;7.98,-4.1,;6.65,-3.33,;5.32,-4.1,;5.32,-5.64,;6.65,-6.41,;3.98,-3.33,;2.65,-4.1,;1.32,-3.33,;1.32,-1.79,;2.65,-1.02,;3.98,-1.79,;-.02,-1.02,;-.02,.52,;-1.35,1.29,;-2.69,.52,;-4.15,.99,;-5.06,-.25,;-4.15,-1.5,;-2.69,-1.02,;-1.35,-1.79,;-6.59,-.25,;-7.37,-1.59,;-7.37,1.08,;-8.91,1.08,;-9.67,2.41,;-11.22,2.41,;-11.99,3.75,;-11.22,5.08,;-11.99,6.41,;-11.59,7.9,;-11.19,9.39,;-10.25,7.13,;-13.13,7.9,;-9.67,5.08,;-8.91,3.75,)| | ||
| Structure | 
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