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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209515 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM209515 | |||
| n/a | |||
| Name | BDBM209515 | ||
| Synonyms: | US9271969, 3 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C29H26F3N3O4 | ||
| Mol. Mass. | 537.5296 | ||
| SMILES | OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)Nc1ccc(OC(F)(F)F)cc1 |r,wD:4.3,(9.01,4.57,;7.67,3.8,;6.34,4.57,;7.67,2.26,;6.34,1.49,;5.01,2.26,;3.67,1.49,;3.67,-.05,;5.01,-.82,;6.34,-.05,;2.34,-.82,;2.34,-2.36,;1.01,-3.13,;-.33,-2.36,;-.33,-.82,;1.01,-.05,;-1.66,-3.13,;-1.66,-4.67,;-2.99,-5.44,;-4.33,-4.67,;-5.79,-5.14,;-6.7,-3.9,;-5.79,-2.65,;-4.33,-3.13,;-2.99,-2.36,;-8.24,-3.9,;-9.01,-5.23,;-9.01,-2.56,;-8.24,-1.23,;-6.7,-1.23,;-5.93,.1,;-6.67,1.48,;-5.9,2.82,;-6.67,4.15,;-7.44,5.49,;-5.34,4.92,;-8,3.38,;-8.24,1.44,;-9.01,.1,)| | ||
| Structure | 
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