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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209533 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM209533 | |||
| n/a | |||
| Name | BDBM209533 | ||
| Synonyms: | US9271969, 21 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H29F2N3O3 | ||
| Mol. Mass. | 529.5771 | ||
| SMILES | OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NC1(CC1)c1cc(F)ccc1F |r,wD:4.3,(11.21,-5.75,;9.88,-4.98,;9.88,-3.44,;8.55,-5.75,;7.21,-4.98,;7.21,-3.44,;5.88,-2.67,;4.55,-3.44,;4.55,-4.98,;5.88,-5.75,;3.21,-2.67,;1.88,-3.44,;.55,-2.67,;.55,-1.13,;1.88,-.36,;3.21,-1.13,;-.79,-.36,;-.79,1.18,;-2.12,1.95,;-3.46,1.18,;-4.92,1.66,;-5.82,.41,;-4.92,-.83,;-3.46,-.36,;-2.12,-1.13,;-7.36,.41,;-8.13,-.92,;-8.13,1.75,;-9.67,1.75,;-10.44,.41,;-11.21,1.75,;-8.9,3.08,;-7.36,3.08,;-6.59,4.41,;-5.05,4.41,;-7.36,5.75,;-8.9,5.75,;-9.67,4.41,;-11.21,4.41,)| | ||
| Structure | 
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