Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209549 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
| ||
| BDBM209549 | |||
| n/a | |||
| Name | BDBM209549 | ||
| Synonyms: | US9271969, 37 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C30H31N3O3 | ||
| Mol. Mass. | 481.5854 | ||
| SMILES | Cc1ccccc1CNC(=O)c1cn2cc(ccc2n1)-c1ccc(cc1)C1CC[C@H](CC(O)=O)CC1 |r,wD:29.33,(-11.99,1.75,;-11.22,3.08,;-11.99,4.41,;-11.22,5.75,;-9.68,5.75,;-8.91,4.41,;-9.68,3.08,;-8.91,1.75,;-7.37,1.75,;-6.6,.41,;-7.37,-.92,;-5.06,.41,;-4.15,-.83,;-2.69,-.36,;-1.35,-1.13,;-.02,-.36,;-.02,1.18,;-1.35,1.95,;-2.69,1.18,;-4.15,1.66,;1.32,-1.13,;1.32,-2.67,;2.65,-3.44,;3.98,-2.67,;3.98,-1.13,;2.65,-.36,;5.32,-3.44,;6.65,-2.67,;7.98,-3.44,;7.98,-4.98,;9.32,-5.75,;10.65,-4.98,;11.99,-5.75,;10.65,-3.44,;6.65,-5.75,;5.32,-4.98,)| | ||
| Structure | 
| ||