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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209561 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM209561 | |||
| n/a | |||
| Name | BDBM209561 | ||
| Synonyms: | US9271969, 49 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H25ClFN3O3S | ||
| Mol. Mass. | 526.022 | ||
| SMILES | OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1cn2cc(nc2s1)C(=O)NCc1ccc(F)c(Cl)c1 |r,wU:7.10,wD:4.3,(11.19,-2,;9.72,-2,;8.95,-.67,;8.95,-3.33,;7.41,-3.33,;6.64,-2,;5.1,-2,;4.33,-3.33,;5.1,-4.67,;6.64,-4.67,;2.79,-3.33,;2.02,-4.67,;.48,-4.67,;-.29,-3.33,;.48,-2,;2.02,-2,;-1.83,-3.33,;-2.74,-4.58,;-4.2,-4.1,;-5.66,-4.58,;-6.57,-3.33,;-5.66,-2.09,;-4.2,-2.56,;-2.74,-2.09,;-8.11,-3.33,;-8.88,-4.67,;-8.88,-2,;-8.11,-.67,;-8.88,.67,;-10.42,.67,;-11.19,2,;-10.42,3.33,;-11.19,4.67,;-8.88,3.33,;-8.11,4.67,;-8.11,2,)| | ||
| Structure | 
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