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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209569 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM209569 | |||
| n/a | |||
| Name | BDBM209569 | ||
| Synonyms: | US9271969, 57 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C28H29N3O4S | ||
| Mol. Mass. | 503.613 | ||
| SMILES | COc1ccc(CNC(=O)c2cn3cc(sc3n2)-c2ccc(cc2)C2CC[C@H](CC(O)=O)CC2)cc1 |r,wD:27.30,(-12.76,4.67,;-11.22,4.67,;-10.45,3.33,;-8.91,3.33,;-8.14,2,;-8.91,.67,;-8.14,-.67,;-8.91,-2,;-8.14,-3.33,;-8.91,-4.67,;-6.6,-3.33,;-5.7,-4.58,;-4.24,-4.1,;-2.77,-4.58,;-1.87,-3.33,;-2.77,-2.09,;-4.24,-2.56,;-5.7,-2.09,;-.33,-3.33,;.44,-2,;1.98,-2,;2.75,-3.33,;1.98,-4.67,;.44,-4.67,;4.29,-3.33,;5.06,-2,;6.6,-2,;7.37,-3.33,;8.91,-3.33,;9.68,-2,;11.22,-2,;8.91,-.67,;6.6,-4.67,;5.06,-4.67,;-10.45,.67,;-11.22,2,)| | ||
| Structure | 
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