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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209572 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM209572 | |||
| n/a | |||
| Name | BDBM209572 | ||
| Synonyms: | US9271969, 60 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H23ClFN3O3S | ||
| Mol. Mass. | 511.996 | ||
| SMILES | OC(=O)C[C@H]1CCC(CC1)c1ccc(cc1)-c1cn2cc(nc2s1)C(=O)Nc1ccc(F)c(Cl)c1 |r,wD:4.3,(10.07,-1.33,;8.53,-1.33,;7.76,,;7.76,-2.67,;6.22,-2.67,;5.45,-1.33,;3.91,-1.33,;3.14,-2.67,;3.91,-4,;5.45,-4,;1.6,-2.67,;.83,-4,;-.71,-4,;-1.48,-2.67,;-.71,-1.33,;.83,-1.33,;-3.02,-2.67,;-3.93,-3.91,;-5.39,-3.44,;-6.85,-3.91,;-7.76,-2.67,;-6.85,-1.42,;-5.39,-1.9,;-3.93,-1.42,;-9.3,-2.67,;-10.07,-4,;-10.07,-1.33,;-9.3,,;-7.76,,;-6.99,1.33,;-7.76,2.67,;-6.99,4,;-9.3,2.67,;-10.07,4,;-10.07,1.33,)| | ||
| Structure | 
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