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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209574 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM209574 | |||
| n/a | |||
| Name | BDBM209574 | ||
| Synonyms: | US9271969, 62 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H25ClFN3O3S | ||
| Mol. Mass. | 526.022 | ||
| SMILES | OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1cn2cc(nc2s1)C(=O)NCc1c(F)cccc1Cl |r,wU:7.10,wD:4.3,(12.38,2.67,;10.84,2.67,;10.07,4,;10.07,1.33,;8.53,1.33,;7.76,2.67,;6.22,2.67,;5.45,1.33,;6.22,,;7.76,,;3.91,1.33,;3.14,2.67,;1.6,2.67,;.83,1.33,;1.6,,;3.14,,;-.71,1.33,;-1.62,.09,;-3.08,.56,;-4.54,.09,;-5.45,1.33,;-4.54,2.58,;-3.08,2.1,;-1.62,2.58,;-6.99,1.33,;-7.76,2.67,;-7.76,,;-9.3,,;-10.07,-1.33,;-11.61,-1.33,;-12.38,,;-12.38,-2.67,;-11.61,-4,;-10.07,-4,;-9.3,-2.67,;-7.76,-2.67,)| | ||
| Structure | 
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