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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209576 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM209576 | |||
| n/a | |||
| Name | BDBM209576 | ||
| Synonyms: | US9271969, 64 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H24ClF2N3O3S | ||
| Mol. Mass. | 544.013 | ||
| SMILES | OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1cn2cc(nc2s1)C(=O)NCc1c(F)cc(Cl)cc1F |r,wU:7.10,wD:4.3,(12.38,3.33,;10.84,3.33,;10.07,4.67,;10.07,2,;8.53,2,;7.76,3.33,;6.22,3.33,;5.45,2,;6.22,.67,;7.76,.67,;3.91,2,;3.14,3.33,;1.6,3.33,;.83,2,;1.6,.67,;3.14,.67,;-.71,2,;-1.62,.75,;-3.08,1.23,;-4.54,.75,;-5.45,2,;-4.54,3.25,;-3.08,2.77,;-1.62,3.25,;-6.99,2,;-7.76,3.33,;-7.76,.67,;-9.3,.67,;-10.07,-.67,;-11.61,-.67,;-12.38,.67,;-12.38,-2,;-11.61,-3.33,;-12.38,-4.67,;-10.07,-3.33,;-9.3,-2,;-7.76,-2,)| | ||
| Structure | 
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