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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Diacylglycerol O-acyltransferase 1 | ||
| Ligand | BDBM209577 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Inhibition Assay | ||
| pH | 7.4±n/a | ||
| Temperature | 298.15±n/a K | ||
| IC50 | <10±n/a nM | ||
| Comments | extracted | ||
| Citation |  Kim, D; Bok, J; Shin, S Compounds as inhibitors of diacylglycerol O-acyltransferase type 1 enzyme US Patent US9271969 Publication Date 3/1/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Diacylglycerol O-acyltransferase 1 | |||
| Name: | Diacylglycerol O-acyltransferase 1 | ||
| Synonyms: | ACAT-related gene product 1 | AGRP1 | Acyl coA-diacylglycerol acyl transferase 1 (DGAT1) | DGAT | DGAT1 | DGAT1_HUMAN | Diacylglycerol Acyltransferase (DGAT1) | Diacylglycerol O-acyltransferase 1 | Diacylglycerol O-acyltransferase 1 (DGAT1) | Diglyceride acyltransferase | ||
| Type: | Protein | ||
| Mol. Mass.: | 55297.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O75907 | ||
| Residue: | 488 | ||
| Sequence: |
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| BDBM209577 | |||
| n/a | |||
| Name | BDBM209577 | ||
| Synonyms: | US9271969, 65 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C31H33N3O3 | ||
| Mol. Mass. | 495.612 | ||
| SMILES | CC(C)([C@H]1CCC(CC1)c1ccc(cc1)-c1ccc2nc(cn2c1)C(=O)NCc1ccccc1)C(O)=O |r,wD:3.2,(8.55,-6.41,;9.32,-5.08,;10.09,-6.41,;7.98,-4.31,;7.98,-2.77,;6.65,-2,;5.32,-2.77,;5.32,-4.31,;6.65,-5.08,;3.98,-2,;2.65,-2.77,;1.32,-2,;1.32,-.46,;2.65,.31,;3.98,-.46,;-.02,.31,;-.02,1.85,;-1.35,2.62,;-2.69,1.85,;-4.15,2.33,;-5.06,1.08,;-4.15,-.17,;-2.69,.31,;-1.35,-.46,;-6.6,1.08,;-7.37,-.25,;-7.37,2.41,;-8.91,2.41,;-9.68,3.75,;-8.91,5.08,;-9.68,6.41,;-11.22,6.41,;-11.99,5.08,;-11.22,3.75,;10.65,-4.31,;11.99,-5.08,;10.65,-2.77,)| | ||
| Structure | 
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