Reaction Details |
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Target | Fatty acid-binding protein 5 |
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Ligand | BDBM212457 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Time Resolved-Fluorescence Energy Transfer (TR-FRET) Assay |
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pH | 7.5±n/a |
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Temperature | 298.15±n/a K |
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IC50 | 6350±n/a nM |
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Comments | extracted |
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Citation | Buettelmann, B; Ceccarelli, SM; Conte, A; Kuehne, H; Kuhn, B; Neidhart, W; Obst Sander, U; Richter, H Urea derivatives and their use as fatty-acid binding protein (FABP) inhibitors US Patent US9278918 Publication Date 3/8/2016 |
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More Info.: | Get all data from this article, Assay Method |
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Fatty acid-binding protein 5 |
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Name: | Fatty acid-binding protein 5 |
Synonyms: | FABP5 | FABP5_HUMAN | Fatty acid binding protein epidermal | Fatty acid-binding protein 5 (FABP5) |
Type: | Enzyme |
Mol. Mass.: | 15164.79 |
Organism: | Homo sapiens (Human) |
Description: | Q01469 |
Residue: | 135 |
Sequence: | MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL
KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC
VMNNVTCTRIYEKVE
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BDBM212457 |
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n/a |
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Name | BDBM212457 |
Synonyms: | US9278918, 47 |
Type | Small organic molecule |
Emp. Form. | C20H19F3N2O3 |
Mol. Mass. | 392.3717 |
SMILES | OC(=O)C1(CCCC1)NC(=O)Nc1cc(ccc1-c1ccccc1)C(F)(F)F |
Structure |
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