| Reaction Details |
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 | Report a problem with these data |
| Target | Egl nine homolog 1 [179-426] |
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| Ligand | BDBM102346 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Activity Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | 12000±n/a nM |
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| Comments | extracted |
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| Citation |  Shalwitz, R; Gardner, JH Methods for increasing the stabilization of hypoxia inducible factor-α US Patent US9278930 Publication Date 3/8/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Egl nine homolog 1 [179-426] |
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| Name: | Egl nine homolog 1 [179-426] |
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| Synonyms: | C1orf12 | EGLN1 | EGLN1_HUMAN | Hypoxia-inducible factor prolyl hydroxylase 2 (HIFPH2) |
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| Type: | n/a |
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| Mol. Mass.: | 27759.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EGLN-1-179/426 |
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| Residue: | 248 |
|---|
| Sequence: | LRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDG
QLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKA
MVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEP
KFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPS
DSVGKDVF
|
|
|
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| BDBM102346 |
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| n/a |
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| Name | BDBM102346 |
|---|
| Synonyms: | US10562854, No. D14 | US8536181, D14 | US9278930, D14 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H22ClN5O4S |
|---|
| Mol. Mass. | 475.948 |
|---|
| SMILES | Cc1ccc(cc1)S(=O)(=O)n1ccc(CN2CCN(CC2)c2ccc(Cl)nn2)c(O)c1=O |
|---|
| Structure | 
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