| Reaction Details |
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 | Report a problem with these data |
| Target | Aldehyde dehydrogenase, mitochondrial |
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| Ligand | BDBM223465 |
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| Substrate/Competitor | BDBM60952 |
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| Meas. Tech. | Inhibiton Assay |
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| pH | 7.5±n/a |
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| IC50 | 7300±n/a nM |
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| Comments | extracted |
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| Citation |  Hurley, TD Regulators of aldehyde dehydrogenase ALDH3A1 and related therapeutic methods US Patent US9320722 Publication Date 4/26/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Aldehyde dehydrogenase, mitochondrial |
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| Name: | Aldehyde dehydrogenase, mitochondrial |
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| Synonyms: | ALDH class 2 | ALDH-E2 | ALDH2 | ALDH2_HUMAN | ALDHI | ALDM | Aldehyde dehydrogenase (ALDH2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 56382.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P05091 |
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| Residue: | 517 |
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| Sequence: | MLRAAARFGPRLGRRLLSAAATQAVPAPNQQPEVFCNQIFINNEWHDAVSRKTFPTVNPS
TGEVICQVAEGDKEDVDKAVKAARAAFQLGSPWRRMDASHRGRLLNRLADLIERDRTYLA
ALETLDNGKPYVISYLVDLDMVLKCLRYYAGWADKYHGKTIPIDGDFFSYTRHEPVGVCG
QIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPG
FGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADM
DWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGP
QVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGP
VMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQS
PFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS
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| BDBM223465 |
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| BDBM60952 |
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| Name | BDBM223465 |
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| Synonyms: | US9320722, CD13 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17FN2OS |
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| Mol. Mass. | 328.404 |
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| SMILES | CCn1c(cs\c1=N\c1ccccc1)-c1ccc(OC)c(F)c1 |
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| Structure | 
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