| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-3 |
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| Ligand | BDBM224972 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Assay |
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| IC50 | 170.393±n/a nM |
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| Citation |  Wang, H; Cee, VJ; Herberich, BJ; Jackson, CL; Lanman, BA; Nixey, T; Pettus, LH; Reed, AB; Wu, B; Wurz, R; Tasker, A Azole compounds as PIM inhibitors US Patent US9321756 Publication Date 4/26/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Serine/threonine-protein kinase pim-3 |
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| Name: | Serine/threonine-protein kinase pim-3 |
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| Synonyms: | PIM3 | PIM3_HUMAN | Serine/threonine-protein kinase pim-3 (PIM3) |
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| Type: | Protein |
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| Mol. Mass.: | 35888.19 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q86V86 |
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| Residue: | 326 |
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| Sequence: | MLLSKFGSLAHLCGPGGVDHLPVKILQPAKADKESFEKAYQVGAVLGSGGFGTVYAGSRI
ADGLPVAVKHVVKERVTEWGSLGGATVPLEVVLLRKVGAAGGARGVIRLLDWFERPDGFL
LVLERPEPAQDLFDFITERGALDEPLARRFFAQVLAAVRHCHSCGVVHRDIKDENLLVDL
RSGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSATVWSLGVLLYDMVC
GDIPFEQDEEILRGRLLFRRRVSPECQQLIRWCLSLRPSERPSLDQIAAHPWMLGADGGV
PESCDLRLCTLDPDDVASTTSSSESL
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| BDBM224972 |
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| n/a |
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| Name | BDBM224972 |
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| Synonyms: | US9321756, 239 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12FN5S |
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| Mol. Mass. | 325.363 |
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| SMILES | CNc1nnc(s1)-c1ccc2[nH]cc(-c3cccc(F)n3)c2c1 |
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| Structure | 
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