| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-galactosidase [24-677] |
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| Ligand | BDBM228802 |
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| Substrate/Competitor | 4-Methylumbelliferyl-β-D-galactopyranoside |
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| Meas. Tech. | β-Gal Inhibitory Assay |
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| pH | 4.5±n/a |
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| Temperature | 310.15±n/a K |
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| Ki | 6.83e+4±n/a nM |
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| Citation |  Suzuki, H; Ohto, U; Higaki, K; Mena-Barragán, T; Aguilar-Moncayo, M; Ortiz Mellet, C; Nanba, E; Garcia Fernandez, JM; Suzuki, Y; Shimizu, T Structural basis of pharmacological chaperoning for human ß-galactosidase. J Biol Chem289:14560-8 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-galactosidase [24-677] |
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| Name: | Beta-galactosidase [24-677] |
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| Synonyms: | BGAL_HUMAN | ELNR1 | GLB1 | beta-Galactosidase (β-Gal) |
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| Type: | Enzyme |
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| Mol. Mass.: | 73588.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human β-Gal (24-677 aa) |
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| Residue: | 654 |
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| Sequence: | LRNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTY
VPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKE
SILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFL
QKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGP
LINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSP
YAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLK
TVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRA
YVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSS
NILTDWTIFPLDTEDAVRSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIP
DLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEW
APCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV
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| BDBM228802 |
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| 4-Methylumbelliferyl-β-D-galactopyranoside |
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| Name | BDBM228802 |
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| Synonyms: | 5N,6S-(N'-butyliminomethylidene)-6-thio-1-deoxygalactonojirimycin | 6S-NBI-DGJ |
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| Type | Small organic molecule |
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| Emp. Form. | C11H20N2O3S |
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| Mol. Mass. | 260.353 |
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| SMILES | CCCC\N=C1/SC[C@@H]2[C@H](O)[C@H](O)[C@@H](O)CN12 |
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| Structure | 
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