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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine-protein kinase ATM | ||
| Ligand | BDBM245478 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Cellular Assay | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 0.24±n/a nM | ||
| Comments | extracted | ||
| Citation |  Barlaam, BC; Pike, KG Imidazo[4,5-c]quinolin-2-one compounds and their use in treating Cancer US Patent US9428503 Publication Date 8/30/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine-protein kinase ATM | |||
| Name: | Serine-protein kinase ATM | ||
| Synonyms: | A-T mutated | ATM | ATM_HUMAN | Ataxia telangiectasia mutated | ||
| Type: | Protein | ||
| Mol. Mass.: | 350696.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q13315 | ||
| Residue: | 3056 | ||
| Sequence: |
| ||
| BDBM245478 | |||
| n/a | |||
| Name | BDBM245478 | ||
| Synonyms: | US9428503, 5 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H29N5O3 | ||
| Mol. Mass. | 447.5295 | ||
| SMILES | CN(C)CCCOc1ccc(cn1)-c1ccc2ncc3n(C)c(=O)n([C@@H]4C[C@H](O)C4)c3c2c1 |r,wD:25.25,27.28,(-9.98,.47,;-8.65,1.24,;-8.65,2.78,;-7.32,.47,;-5.98,1.24,;-4.65,.47,;-3.32,1.24,;-1.98,.47,;-.65,1.24,;.68,.47,;.68,-1.07,;-.65,-1.84,;-1.98,-1.07,;2.02,-1.84,;2.02,-3.38,;3.35,-4.15,;4.69,-3.38,;6.02,-4.15,;7.35,-3.38,;7.35,-1.84,;8.5,-.81,;9.98,-1.21,;7.87,.6,;8.64,1.93,;6.34,.43,;5.25,1.52,;3.71,1.52,;3.71,3.06,;2.62,4.15,;5.25,3.06,;6.02,-1.07,;4.69,-1.84,;3.35,-1.07,)| | ||
| Structure | 
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