Reaction Details | |||
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Target | Serine-protein kinase ATM | ||
Ligand | BDBM245499 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Cellular Assay | ||
Temperature | 310.15±n/a K | ||
IC50 | 0.418±n/a nM | ||
Comments | extracted | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Serine-protein kinase ATM | |||
Name: | Serine-protein kinase ATM | ||
Synonyms: | A-T mutated | ATM | ATM_HUMAN | Ataxia telangiectasia mutated | ||
Type: | Protein | ||
Mol. Mass.: | 350696.72 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q13315 | ||
Residue: | 3056 | ||
Sequence: |
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BDBM245499 | |||
n/a | |||
Name | BDBM245499 | ||
Synonyms: | US9428503, 27 | ||
Type | Small organic molecule | ||
Emp. Form. | C28H32FN5O3 | ||
Mol. Mass. | 505.5838 | ||
SMILES | CO[C@H]1C[C@H](C1)n1c2c(cnc3cc(F)c(cc23)-c2ccc(OCCCN3CCCC3)nc2)n(C)c1=O |r,wD:4.6,2.1,(4.18,4.94,;3.41,3.61,;4.18,2.27,;4.18,.73,;5.72,.73,;5.72,2.27,;6.81,-.35,;6.49,-1.86,;7.82,-2.63,;7.82,-4.17,;6.49,-4.94,;5.15,-4.17,;3.82,-4.94,;2.49,-4.17,;1.15,-4.94,;2.49,-2.63,;3.82,-1.86,;5.15,-2.63,;1.15,-1.86,;1.15,-.32,;-.18,.45,;-1.51,-.32,;-2.85,.45,;-4.18,-.32,;-5.52,.45,;-6.85,-.32,;-8.18,.45,;-8.18,1.99,;-9.65,2.46,;-10.55,1.22,;-9.65,-.03,;-1.51,-1.86,;-.18,-2.63,;8.97,-1.6,;10.55,-2.03,;8.34,-.19,;9.11,1.14,)| | ||
Structure | ![]() |