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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine-protein kinase ATM | ||
| Ligand | BDBM245507 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Cellular Assay | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 0.589±n/a nM | ||
| Comments | extracted | ||
| Citation |  Barlaam, BC; Pike, KG Imidazo[4,5-c]quinolin-2-one compounds and their use in treating Cancer US Patent US9428503 Publication Date 8/30/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine-protein kinase ATM | |||
| Name: | Serine-protein kinase ATM | ||
| Synonyms: | A-T mutated | ATM | ATM_HUMAN | Ataxia telangiectasia mutated | ||
| Type: | Protein | ||
| Mol. Mass.: | 350696.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q13315 | ||
| Residue: | 3056 | ||
| Sequence: |
| ||
| BDBM245507 | |||
| n/a | |||
| Name | BDBM245507 | ||
| Synonyms: | US9428503, 35 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H31N5O3 | ||
| Mol. Mass. | 473.5667 | ||
| SMILES | CO[C@H]1C[C@H](C1)n1c2c(cnc3ccc(cc23)-c2ccc(OCCCN3CCCC3)nc2)[nH]c1=O |r,wD:4.6,2.1,(4.21,4.9,;3.81,3.41,;4.9,2.32,;4.9,.78,;6.44,.78,;6.44,2.32,;7.53,-.31,;7.21,-1.82,;8.54,-2.59,;8.54,-4.13,;7.21,-4.9,;5.88,-4.13,;4.54,-4.9,;3.21,-4.13,;3.21,-2.59,;4.54,-1.82,;5.88,-2.59,;1.87,-1.82,;1.87,-.28,;.54,.49,;-.79,-.28,;-2.13,.49,;-3.46,-.28,;-4.79,.49,;-6.13,-.28,;-7.46,.49,;-7.46,2.03,;-8.93,2.51,;-9.83,1.26,;-8.93,.02,;-.79,-1.82,;.54,-2.59,;9.69,-1.56,;9.06,-.15,;9.83,1.19,)| | ||
| Structure | 
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