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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine-protein kinase ATM | ||
| Ligand | BDBM245514 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Cellular Assay | ||
| Temperature | 310.15±n/a K | ||
| IC50 | 0.249±n/a nM | ||
| Comments | extracted | ||
| Citation |  Barlaam, BC; Pike, KG Imidazo[4,5-c]quinolin-2-one compounds and their use in treating Cancer US Patent US9428503 Publication Date 8/30/2016 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine-protein kinase ATM | |||
| Name: | Serine-protein kinase ATM | ||
| Synonyms: | A-T mutated | ATM | ATM_HUMAN | Ataxia telangiectasia mutated | ||
| Type: | Protein | ||
| Mol. Mass.: | 350696.72 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q13315 | ||
| Residue: | 3056 | ||
| Sequence: |
| ||
| BDBM245514 | |||
| n/a | |||
| Name | BDBM245514 | ||
| Synonyms: | US9428503, 42 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C25H29N5O3 | ||
| Mol. Mass. | 447.5295 | ||
| SMILES | CNCCCOc1ccc(cn1)-c1ccc2ncc3n(C)c(=O)n([C@@H]4C[C@@H](C4)OC)c3c2c1 |r,wD:24.24,26.29,(-9.91,.47,;-8.57,1.24,;-7.24,.47,;-5.91,1.24,;-4.57,.47,;-3.24,1.24,;-1.91,.47,;-.57,1.24,;.76,.47,;.76,-1.07,;-.57,-1.84,;-1.91,-1.07,;2.1,-1.84,;2.1,-3.38,;3.43,-4.15,;4.76,-3.38,;6.1,-4.15,;7.43,-3.38,;7.43,-1.84,;8.57,-.81,;9.91,-1.58,;7.95,.6,;8.72,1.93,;6.42,.43,;5.33,1.52,;3.79,1.52,;3.79,3.06,;5.33,3.06,;2.7,4.15,;1.21,3.75,;6.1,-1.07,;4.76,-1.84,;3.43,-1.07,)| | ||
| Structure | 
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