| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytochrome P450 1A2 |
|---|
| Ligand | BDBM247990 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Cytochrome P450 Inhibition |
|---|
| Temperature | 310.15±n/a K |
|---|
| IC50 | >10000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Bilcer, GM; Ng, R Quinuclidines for modulating alpha 7 activity US Patent US9434724 Publication Date 9/6/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytochrome P450 1A2 |
|---|
| Name: | Cytochrome P450 1A2 |
|---|
| Synonyms: | CP1A2_HUMAN | CYP1A2 | CYPIA2 | Cholesterol 25-hydroxylase | Cytochrome P(3)450 | Cytochrome P450 1A | Cytochrome P450 1A2 (CYP1A2) | Cytochrome P450 4 | Cytochrome P450-P3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 58423.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P05177 |
|---|
| Residue: | 516 |
|---|
| Sequence: | MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKN
PHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDG
QSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELM
AGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFP
ILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGN
LIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLS
DRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPEL
WEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLE
FSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN
|
|
|
|---|
| BDBM247990 |
|---|
| n/a |
|---|
| Name | BDBM247990 |
|---|
| Synonyms: | US9434724, 46 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H19ClN2O3 |
|---|
| Mol. Mass. | 334.797 |
|---|
| SMILES | Oc1cc(Cl)c2c(c[nH]c2c1)C(=O)OCC12CCN(CC1)CC2 |
|---|
| Structure | 
|
|---|
Search and Browse
