Reaction Details |
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Target | Baculoviral IAP repeat-containing protein 2 [174-256] |
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Ligand | BDBM298425 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Enzyme Inhibition |
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IC50 | 10.00±n/a nM |
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Citation | Baker, TM; Fyfe, MC; Jones, G; Thom, SM Kinase inhibitors US Patent US10392346 Publication Date 8/27/2019 |
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More Info.: | Get all data from this article, Assay Method |
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Baculoviral IAP repeat-containing protein 2 [174-256] |
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Name: | Baculoviral IAP repeat-containing protein 2 [174-256] |
Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | CIAP Bir2 | MIHB | RNF48 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 9527.07 |
Organism: | Homo sapiens (Human) |
Description: | Q13490[174-256] |
Residue: | 83 |
Sequence: | TNPYSYAMSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPK
DDAMSEHRRHFPNCPFLENSLET
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BDBM298425 |
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n/a |
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Name | BDBM298425 |
Synonyms: | 4-[[4-[[4-[[5-tert-butyl-3-(methanesulfonamido)-2-methoxy-phenyl]carbamoylamino]-1-naphthyl]oxy]-2-pyridyl]amino]-2,6-dimethoxy-N-(2-morpholinoethyl)benzamide | US10125100, Example 17(ae) | US10392346, Example 17(ae) | US10941115, Example 17(ae) | US9751837, Example 17(ae) |
Type | Small organic molecule |
Emp. Form. | C43H51N7O9S |
Mol. Mass. | 841.972 |
SMILES | COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OC)c1C(=O)NCCN1CCOCC1 |
Structure |
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