Reaction Details |
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Target | Baculoviral IAP repeat-containing protein 2 [174-256] |
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Ligand | BDBM298449 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Enzyme Inhibition |
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IC50 | 4.00±n/a nM |
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Citation | Baker, TM; Fyfe, MC; Jones, G; Thom, SM Kinase inhibitors US Patent US10392346 Publication Date 8/27/2019 |
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More Info.: | Get all data from this article, Assay Method |
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Baculoviral IAP repeat-containing protein 2 [174-256] |
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Name: | Baculoviral IAP repeat-containing protein 2 [174-256] |
Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | CIAP Bir2 | MIHB | RNF48 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 9527.07 |
Organism: | Homo sapiens (Human) |
Description: | Q13490[174-256] |
Residue: | 83 |
Sequence: | TNPYSYAMSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPK
DDAMSEHRRHFPNCPFLENSLET
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BDBM298449 |
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n/a |
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Name | BDBM298449 |
Synonyms: | 2-(2-(2-(4-((4-((4-(3-(5-(tert-butyl)-2-methoxy-3-(methylsulfonamido)phenyl)ureido)-naphthalen-1-yl)oxy)pyridin-2-yl)amino)-2,6-dimethoxybenzamido)ethoxy)ethoxy)ethyl dihydrogen phosphate | US10125100, Example 47 | US10392346, Example 47 | US10941115, Example 47 | US9751837, Example 47 |
Type | Small organic molecule |
Emp. Form. | C43H53N6O14PS |
Mol. Mass. | 940.951 |
SMILES | COc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)ccn2)cc(OC)c1C(=O)NCCOCCOCCOP(O)(O)=O |
Structure |
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