| Reaction Details |
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 | Report a problem with these data |
| Target | N-formyl peptide receptor 2 |
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| Ligand | BDBM350556 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | FLIPR |
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| EC50 | 10.00±n/a nM |
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| Citation |  Viswanath, V; Beard, RL; Donello, JE; Hsia, E Use of agonists of formyl peptide receptor 2 for treating dermatological diseases US Patent US10434112 Publication Date 10/8/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| N-formyl peptide receptor 2 |
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| Name: | N-formyl peptide receptor 2 |
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| Synonyms: | ALXR, FPRL1, FPR2 | FMLP-related receptor I FMLP-R-I | FPR2 | FPR2_HUMAN | FPRH1 | FPRL1 | Formyl Peptide Receptor-Like 1 | HM63 | LXA4 receptor | LXA4R | Lipoxin A4 receptor | Lipoxin A4 receptor (LXA4) | RFP | hFPRL |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 38968.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25090 |
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| Residue: | 351 |
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| Sequence: | METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVT
TICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIA
LDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNF
ASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPL
RVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPM
LYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
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| BDBM350556 |
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| n/a |
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| Name | BDBM350556 |
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| Synonyms: | 1-[2-(3-aminopropyl)-3-(4- cyanophenyl)-1-oxo-1,2,3,4- tetrahydroisoquinolin-7-yl]-3- [4-(methylsulfonyl)phenyl]urea | US10208071, Compound 18 | US10434112, Compound 18 | US10799518, Compound 18 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H27N5O4S |
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| Mol. Mass. | 517.599 |
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| SMILES | CS(=O)(=O)c1ccc(NC(=O)Nc2ccc3CC(N(CCCN)C(=O)c3c2)c2ccc(cc2)C#N)cc1 |
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| Structure | 
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