| Reaction Details |
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 | Report a problem with these data |
| Target | Histone deacetylase 11 |
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| Ligand | BDBM421500 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | HDAC Inhibition Assays |
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| IC50 | 3.00±n/a nM |
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| Citation |  Lee, J; Barczak, N; Escobedo, JA; Conti, C; Han, B; Lancia, Jr., DR; Liu, C; Martin, MW; Ng, PY; Rudnitskaya, A; Thomason, JR; Zheng, X Methods using HDAC11 inhibitors US Patent US10508088 Publication Date 12/17/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Histone deacetylase 11 |
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| Name: | Histone deacetylase 11 |
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| Synonyms: | HD11 | HDA11_HUMAN | HDAC11 | Human HDAC11 |
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| Type: | Chromatin regulator; hydrolase; repressor |
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| Mol. Mass.: | 39187.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q96DB2 |
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| Residue: | 347 |
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| Sequence: | MLHTTQLYQHVPETRWPIVYSPRYNITFMGLEKLHPFDAGKWGKVINFLKEEKLLSDSML
VEAREASEEDLLVVHTRRYLNELKWSFAVATITEIPPVIFLPNFLVQRKVLRPLRTQTGG
TIMAGKLAVERGWAINVGGGFHHCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDL
DAHQGNGHERDFMDDKRVYIMDVYNRHIYPGDRFAKQAIRRKVELEWGTEDDEYLDKVER
NIKKSLQEHLPDVVVYNAGTDILEGDRLGGLSISPAGIVKRDELVFRMVRGRRVPILMVT
SGGYQKRTARIIADSILNLFGLGLIGPESPSVSAQNSDTPLLPPAVP
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| BDBM421500 |
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| n/a |
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| Name | BDBM421500 |
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| Synonyms: | US10508088, Example 1-1 | US10508088, ID HDTK010 | US10538496, Compound 1-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H9Cl2N3O3 |
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| Mol. Mass. | 338.146 |
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| SMILES | ONC(=O)c1cccc(Nc2nc3cc(Cl)c(Cl)cc3o2)c1 |
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| Structure | 
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